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Negin Nekahi, MD, PhD

Position
Infectious Disease

Specialty
Internal Medicine
Infectious Disease

Education
University of Washington (Fellowship – Infectious Disease)
University of Washington (Residency – Internal Medicine)
University of Washington, School of Medicine (MD)
University of Washington (PhD)
University of Washington (BS)

Grant Sources
VA Funding, Pharma Funding, Arizona Veterans Research and Education Foundation

Hobbies
Hiking, biking, kayaking, skiing, pretty much anything that gets me outside with fresh air and nature.

Personal Info

I fell in love with science as a sophomore in college when I started in my first research lab. I couldn’t hold a pipette and had no idea how to ask a hypothesis driven question, but I knew I had found a passion. As the year passed and that passion was molded into what it has become today, I find that science- asking a question and answering it all with the goal of helping others is still at the core. My passion for infectious diseases started as a junior in college when I took my first series of virology course and the more, I learned the more I was fascinated. This brought me to my graduate work on the role of Nuclear Factor Kappa B in Human Herpes Virus 8 replication. My post graduate work looked at the role of innate immunity in control vaccinia virus infections. Upon completion of my graduate work and fellowship I transitioned to more translational and outcomes research. I have headed several studies looking at the role of decolonization of S aureus in the ICU and in surgical patients to decrease complications and hospital and surgical site infections. Currently I am a part of several studies evaluating the epidemiology, prevention and treatment of Clostridioides difficile colitis. More recently my work has turned to understanding SARS-CoV-2 epidemiology, prevention, and management of disease. My extensive experience in successfully managed projects, collaborating with other researchers and producing several peer-reviewed abstracts and publications demonstrate my qualifications as a VA investigator. Results from these projects demonstrate my ability and expertise in conducting research, managing and supervising study teams, and engaging in active collaborations.

Notable Publications
Marija Zaric, Pablo D. Becker, Catherine Hervouet, Petya Kalcheva, Andor Doszpoly, Negin Blattman, Barbara Ibarzo Yus, Clement Cocita, Sung-Yun Kwon, Andrew Baker, Graham M Lord, Linda S. Klavinskis.. Skin immunization activates an innate lymphoid cell-monocyte axis regulating CD8+ effector recruitment to mucosal tissues. Nature Communications
Abhishek Bafna, M.S., Raymond Q. Migrino, M.D, Sai R. Gouravajhala1, Negin Blattman, M.D., Ph.D., Felipe Gutierrez, M.D., Jenna Wiens, Ph.D. Novel Spatiotemporal Characterization of Patient Exposure to Clostridium difficile In Predicting Risk of Healthcare-Associated Infection. Submitted Journal of Infectious Diseases.
Al-Jashaami L, Usta Y, Blattman NN, Nanda R. May 2016 Critical care case of the month. Southwest J Pulm Crit Care. 2016 May;12(5):17
Blattman, NN. Treatment of Hepatitis C in patients with HIV and HCV co-infection. February 2015. Federal practitioner
Orme J, Rivera-Bonilla T, Loli A, Blattman, NN. Native Valve Endocarditis due to Ralstonia pickettii: a case report and literature review. January 2015. Case reports in Infectious Diseases.
Blattman NN, Lagunoff M, Blattman JN, Corey L. The role of NF-kappa-B in
Demidenko A, Blattman JN, Blattman NN, Greenberg PD, Nibert ML (2013). Engineering Recombinant Reoviruses to serve as vaccine vectors. Proceedings of the National Academy of Science 110(20), E1867-E1876.
Fantel AG, Stamps LD, Tran TT, Mackler B, Person RE, Nekahi N. (2000) Free radical formation and toxicity in the limb: Teratogenicity of L-NAME: a new mechanistic model of vascular disruption. Teratology 62(4):237.
Fantel AG, Stamps L, Tran TT, Mackler B, Person RE, Nekahi N. (1999) Role of free radicals in the limb teratorgenicity of L-NAME(n(G)-nitro-(L)-arginine methyl ester): a new mechanistic model of vascular disruption. Teratology 60(3):151-160.
Fantel AG, Nekahi N, Shepard TH, Cornel LM, Unis AS, Lemire RJ. (1997) The teratogenicity of N(omega)-nitro-L-ariginine methyl ester (L-NAME), a nitric oxide synthase inhibitor, in rats. Reproductive. Toxicology. 11(5):709-17.
Fantel AG, Stamps LD, Tran TT, Mackler B, Person RE, Nekahi N. (2000) Free radical formation and toxicity in the limb: Teratogenicity of L-NAME: a new mechanistic model of vascular disruption. Teratology 62(4):237.

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