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Samuel Aguayo, MD

Position
Associate Chief of Staff for Research
Chair, Board of Directors, AVREF

Specialty
Pulmonary Medicine Physician

Education
University of Colorado Health Sciences Center, Denver, CO (Pulmonary Medicine)
San Juan Veterans Affairs Medical Center, San Juan, PR (Internal Medicine)
San Juan Veterans Affairs Medical Center, San Juan, PR (Medicine)
University of Puerto Rico, Rio Piedras, PR (B.S.)

Grant Sources
VA Funding

Hobbies
Volunteer for the Arizona Siberian Husky Rescue/Adoption and Rescue Siberian.

Personal Info

My life long professional efforts and personal interests are largely dedicated to the better understanding and the treatment of tobacco-related lung diseases such as lung cancer and chronic obstructive pulmonary disease (COPD), which are devastating among our Veterans. As an extension of my interest in lung cancer, I am excited to serve as the Phoenix VA site Principal Investigator for the collaborative project “Risk Prediction of Lung Cancer in People 40 Years of Age and Older”. Results from this project will hopefully benefit the Veteran population, especially those who served during the Gulf War and in Iraq and/or Afghanistan where risk factors other than smoking may also play a role in their increased susceptibility to develop lung cancer.

This project will enhance the knowledge of risk factors for lung cancer and may significantly contribute to designing effective strategies for targeted and more effective screening of those at the highest risk. My extensive experience in successfully managed projects, collaborating with other researchers and producing several peer-reviewed abstracts and publications demonstrate my qualifications as a VA investigator. Results from these projects demonstrate my ability and expertise in conducting research, managing and supervising study teams, and engaging in active collaborations.

Notable Publications
Henschke CI, Yip R, Ma T, Aguayo SM, Zulueta J, Yankelevitz DF. CT screening for lung cancer: comparison of three baseline screening protocols. European Radiology Published online: December 3, 2018.  https://doi.org/10.1007/s00330-018-5857-5
Graham HT, Rotroff DM, Marvel SW, Buse JB, Havener TM, Wilson AG, Wagner MJ, Motsinger-Reif AA, ACCORD/ACCORDion Investigators.  Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response.  Front Genet 17;7:138, 2016. PubMed PMID: 27775101; PubMed Central PMCID: PMC5013254.
Perez RL, Kimani AP, King TE, Aguayo SM, Roman J.  Bronchoalveolar Lavage Fluid D dimer Levels are Higher and more Prevalent in Black Patients with Pulmonary Sarcoidosis.  Respiration March 9, 2006.  PubMed PMID: 16534178.
Holtzclaw JD, Jack D, Aguayo SM, Eckman JR, Roman J, Hsu LL.  Enhanced Pulmonary and Systemic Response to Endotoxin in Transgenic Sickle Mice.  American Journal of Respiratory and Critical Care Medicine 169(6): 663-665, 2004.  PubMed PMID: 14684557.
Safran ES, Nwiloh VM, Caplan LS, Flenaugh EL, Aguayo SM.  A Clinician’s Guide to the Medical Consequences of Smoking and Evidence-Based Strategies for Tobacco Cessation.  Ethnicity and Disease 13(Supp3) 82-88, 2003.  PubMed PMID: 14552461.
Mannino DM, Petty TL, Aguayo SM, Redd SC.  Low lung function and incident lung cancer in the United States: Data from the first National Health and Nutrition Examination survey follow-up.  Archives of Internal Medicine 163(12): 1475-80, 2003.  PubMed PMID: 12824098.
Michaelson J, Aguayo SM, Roman J.  Idiopathic pulmonary fibrosis: A practical clinical approach for diagnosis and management.  Chest 118: 788-794, 2000.  PubMed PMID: 10988204.

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