While providing high-quality health care to the nation’s Veterans, the VA also conducts research on some of the most difficult challenges facing medical science today. The VA is a world leader in research areas like aging, diabetes, cancer, women’s health, AIDS, stroke, post-traumatic stress disorder and other mental health issues. VA research has improved medical care for Veterans and the nation.
Observational, genetic, and experimental data indicate that triglyceride rich lipoproteins (TRLs) likely participate causally in atherothrombosis. Yet, robust clinical trial evidence that triglyceride (TG) lowering
Due to very high rates of depression and suicide in The Pacific Island Countries (PICs), there is an urgent need to develop new tools and
Pragmatic research clinical trial on the effectiveness of providing diet and exercise guidelines for prevention of obesity and diabetes using social media on smartphones to
Posttraumatic Stress Disorder constitutes a substantial proportion of the burden of illness among veterans. However, current PTSD treatments are not effective for all, and a
VA Cooperative Study CSP #591 is designed to compare the effectiveness of two types of psychotherapy, Prolonged Exposure and Cognitive Processing Therapy, for treating posttraumatic
Pancreatitis forms a much larger part of the clinical burden in VA hospitals than in civilian ones. Alcohol contributes to a large proportion of alcoholic
Apolipoprotein C-III (apoC-III) is an important determinant of dyslipidemia and cardiovascular risk. The Multi-Ethnic Study of Atherosclerosis (MESA) was a large community based cohort study
For critically ill patients who are unable to participate in their own care and decision-making, partnering with their family members is particularly important for improving
The EFFORT Trial is a multicenter, pragmatic, volunteer-driven, registry-based, randomized, clinical trial with an overall hypothesis that comparing a control group reflective of usual care
This study will determine whether 12 weeks of treatment with Lysulin, compared to placebo, causes a reduction from baseline in the plasma levels of glucose,
This study tests the use of a decision aid for Veterans who are facing a decision about surgery for their Abdominal Aortic Aneurysm (AAA). The
The TRAVERSE (Testosterone Replacement therapy for Assessmentof long-term Vascular Events and efficacy ResponSE in hypogonadal men) is a Phase 4, randomized, double-blinded, placebo-controlled, multicenter study
The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study